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The main active ingredient in tegretol-xr, carbamazepine, is an anticonvulsant that works by decreasing nerve impulses that can cause pain and seizures.

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Have a history of bone marrow depressionare allergic to carbamazepine or any of the ingredients in TEGRETOLSee the end of this Medication Guide for a complete list of ingredients in TEGRETOLtake nefazodoneare allergic to medicines called tricyclic antidepressantsTCAsAsk your healthcare provider or pharmacist for a list of these medicines if you are not surehave taken a medicine called a Monoamine Oxidase InhibitorMAOIin the last 14 daysAsk your healthcare provider or pharmacist for a list of these medicines if you are not sure.

Because of the potential for serious adverse reactions in nursing infants from carbamazepinea decision should be made whether to discontinue nursing or to discontinue the drugtaking into account the importance of the drug to the mother.

The relative risk for suicidal thoughts or behavior was higher in clinical trials for epilepsy than in clinical trials for psychiatric or other conditionsbut the absolute risk differences were similar for the epilepsy and psychiatric indications.

ALTHOUGH REPORTS OF TRANSIENT OR PERSISTENT DECREASED PLATELET OR WHITE BLOOD CELL COUNTS ARE NOT UNCOMMON IN ASSOCIATION WITH THE USE OF TEGRETOLDATA ARE NOT AVAILABLE TO ESTIMATE ACCURATELY THEIR INCIDENCE OR OUTCOMEHOWEVERTHE VAST MAJORITY OF THE CASES OF LEUKOPENIA HAVE NOT PROGRESSED TO THE MORE SERIOUS CONDITIONS OF APLASTIC ANEMIA OR AGRANULOCYTOSIS.

Taking TEGRETOL with certain other medicines may cause side effects or affect how well they workDo not start or stop other medicines without talking to your healthcare provider.

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