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ZETIA is indicated as adjunctive therapy to diet for the reduction of elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia.

Clinical studies have demonstrated that elevated levels of total-CLDL-C and Apo Bthe major protein constituent of LDLpromote human atherosclerosisIn additiondecreased levels of HDL-C are associated with the development of atherosclerosisEpidemiologic studies have established that cardiovascular morbidity and mortality vary directly with the level of total-C and LDL-C and inversely with the level of HDL-CLike LDLcholesterol-enriched triglyceride-rich lipoproteinsincluding very-low-density lipoproteinsVLDLintermediate-density lipoproteinsIDLand remnantscan also promote atherosclerosisThe independent effect of raising HDL-C or lowering TG on the risk of coronary and cardiovascular morbidity and mortality has not been determined.

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofliver disease.

You should not use ezetimibe with astatincholesterol medicineZocorLipitorCrestorand othersif:

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